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dc.contributor.authorCornejo, Omar E.l.
dc.contributor.authorYee, Muh-Ching
dc.contributor.authorDomínguez, Víctor
dc.contributor.authorAndrews, Mary
dc.contributor.authorSockell, Alexandra
dc.contributor.authorStrandberg, Erika
dc.contributor.authorLivingstone Ill, Donald
dc.contributor.authorStack, Conrad
dc.contributor.authorRomero, Alberto
dc.contributor.authorUmaharan, Pathmanathan
dc.contributor.authorRoyaert, Stefan
dc.contributor.authorTawari, Nilesh R.
dc.contributor.authorNg, Pauline
dc.contributor.authorGutiérrez, Osman A.
dc.contributor.authorPhillips Mora, Wilbert
dc.contributor.authorMochaitis, Keithanne
dc.contributor.authorBustamante, Carlos D.
dc.contributor.authorMotamayor, Juan C.
dc.date.accessioned2018-11-02T14:26:09Z
dc.date.available2018-11-02T14:26:09Z
dc.date.issued2018
dc.identifier.urihttp://hdl.handle.net/11554/8960
dc.description.abstractDomestication has had a strong impact on the development of modern societies. We sequenced 200 genomes of the chocolate plant Theobroma cacao L. to show for the first time to our knowledge that a single population, the Criollo population, underwent strong domestication ~3600 years ago (95% CI: 2481–13,806 years ago). We also show that during the process of domestication, there was strong selection for genes involved in the metabolism of the colored protectants anthocyanins and the stimulant theobromine, as well as disease resistance genes. Our analyses show that domesticated populations of T. cacao (Criollo) maintain a higher proportion of high-frequency deleterious mutations. We also show for the first time the negative consequences of the increased accumulation of deleterious mutations during domestication on the fitness of individuals (significant reduction in kilograms of beans per hectare per year as Criollo ancestry increases, as estimated from a GLM, P = 0.000425).es_ES
dc.language.isoenes_ES
dc.relation.ispartofCommunications Biology (2018)1:167es_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.titlePopulation genomic analyses of the chocolate tree, Theobroma cacao L., provide insights into its domestication processes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES


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